Education/Career
Residency in psychiatry, Institute of Mental
Health, Beijing Medical University,
(1988-1993 )
Psychiatrist, Institute of Mental Health,
Beijing Medical University, (1993-1998)
Pfizer/Old Age Psychiatry Fellowship, St. George
Hospital, Department of Psychiatry, Melbourne
University, Australia (1996-1997)
Hubert Humphrey Fellowship, School of Public
Health, Johns Hopkins University, USA
(1998-1999)
Head of Geriatric Psychiatric Department,
Institute of Mental Health Peking University,
Associate Professor of Psychiatry, Geriatric
psychiatrist (1999-2001)
Assistant Director, Institute of Mental Health,
Peking University (2000-2001 )
Executive Director, Peking University, Institute
of Mental Health (2001-2004 )
Director, Peking University Institute of Mental
Health (2004-2013)
Major research fields
Dementia, late life depression and psychosis,
substance abuse, first onset schizophrenia,
mental health and HIV/AIDS, bipolar disorders,
neurocognition assessment in neuropsychiatric
disorders.
Publications and Awards
Co-authored more than 165 original articles and
more than 15 book chapters; Editor-in-chief of
Chinese Mental Health Journal and editors of
more than ten domestic and international
peer-reviewed journals
Present Appointments and Titles
President of Chinese Society of Psychiatry
(2013-2015);
Founding president of Chinese Psychiatrist
Association (2005-2007);
Vice Chairman of Alzheimer’s Disease of China
(2014-20017)
CONFERENCE ABSTRACT
Late life depression and psychosis
Depression in the elderly occurs commonly and is
a major public health problem. We believe that
the prevalence rates of depressive disorders
among elderly people range from 0.8% in
community to 5% in primary care clinics to 15%
in nursing homes. Late life depression is also a
heavy burden for public health in this
particular age group. Depressed patients are
consistently more physically and socially
dysfunctional than their peers with chronic
physical conditions. Moreover, late life
depression can shorten the survival of patients.
Psychosocial factors such as bereavement,
lack/loss of social support, low income seem to
play more important roles in the development of
late life depression. However, biological
changes in the brain are the main determination
of causal mechanism in late life depression
although the whole process is not very clear.
Another less common mental disorder in late life
is psychosis. It may include patients of early
onset of schizophrenia age with psychotic
symptoms as well as patients develop psychosis
after 65. The therapeutic strategies against two
types of late life psychosis (early onset vs.
late onset) are quite different. Since the
underlying pathophysiology are different: the
former has more neurodevelopmental abnormalities
while the latter has more neurodegenerative
changes. Moreover the late onset psychosis
demonstrate more visual hallucinations, more
active emotional reactions, less neurocognitive
impairments, and more sensitive to neuroleptics
compared to those with early onset. Physical and
psychosocial factors are also involved in the
development of late life psychosis such as
sensory impairment (e.g. vision or hearing
disability), isolation, and social-economic
deprivation. In summary, late life depression
and psychosis need more integrated input in
terms of trans-disciplinary team working: old
age psychiatrist, clinical psychologist,
geriatricians, psychiatric nurse, social worker,
and physiotherapist.
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